Study links high blood pressure drug to chronic skin disease

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Psoriasis is a chronic skin condition that affects millions of people worldwide. It causes red, itchy, and scaly patches on the skin, most often appearing on the knees, elbows, scalp, and trunk. While there is no cure for psoriasis, treatments can help manage its symptoms and improve quality of life.

The exact cause of psoriasis isn’t fully understood, but it is believed to result from an overactive immune system that triggers inflammation and speeds up skin cell growth.

Symptoms often flare up in cycles, appearing for weeks or months before subsiding or going into remission. Triggers such as stress, infections, cold weather, or certain medications can worsen the condition.

A recent study by scientists at Ewha Woman’s University has found a potential link between high blood pressure medications and an increased risk of developing psoriasis.

High blood pressure, or hypertension, is a common condition that can lead to serious health problems like heart disease and stroke. To manage it, many people take antihypertensive drugs, including:

  • ACE inhibitors: Relax blood vessels by blocking the production of a hormone called angiotensin II.
  • Beta-blockers: Lower blood pressure by slowing the heart rate and reducing the force of heart contractions.
  • Calcium-channel blockers: Relax blood vessels by decreasing the amount of calcium that enters the heart and blood vessel walls.
  • Diuretics: Help the body eliminate excess salt and water to reduce blood pressure.

The researchers reviewed data from 13 studies and found that some of these medications—particularly beta-blockers, calcium-channel blockers, ACE inhibitors, and thiazide diuretics—might increase the likelihood of developing psoriasis.

They suggest that these drugs could influence the immune system or disrupt the skin’s natural barrier, making it more vulnerable to inflammation.

While the findings do not prove that high blood pressure drugs directly cause psoriasis, they raise important considerations for patients and doctors. People taking these medications should be aware of the potential risk and monitor their skin for signs of psoriasis, such as persistent redness, scaling, or itchiness.

For those who develop psoriasis, treatment options include:

  • Topical ointments: Creams and lotions that reduce inflammation and slow skin cell growth.
  • Light therapy: Exposure to controlled amounts of natural or artificial ultraviolet light.
  • Medications: Drugs that target the immune system to reduce inflammation.

Managing both psoriasis and high blood pressure can be challenging, but it is essential for overall health. Lifestyle changes like eating a balanced diet, exercising regularly, and reducing stress can support treatment for both conditions.

Patients should always consult their healthcare provider before making any changes to their medications or treatment plans.

The study, led by Dr. Hye Sun Gwak and published in the British Journal of Clinical Pharmacology, highlights the need for more research to understand the connection between antihypertensive drugs and psoriasis. Meanwhile, these findings may help guide doctors in making personalized decisions for their patients.

For those interested in natural approaches to health, some studies suggest that fasting could help reverse high blood pressure, and olive oil might reduce blood pressure in healthy individuals.

Similarly, research on skin health points to potential benefits of Vitamin B3 in preventing skin cancers, though dietary choices like high fish intake may increase the risk of certain skin conditions.

This research underscores the importance of taking a holistic approach to health, considering how treatments for one condition might influence others. For people managing high blood pressure and psoriasis, awareness and proactive care can make a significant difference.

If you care about high blood pressure, please read studies about potatoes and high blood pressure, and top 10 choices for a blood pressure-friendly diet

For more information about high blood pressure, please see recent studies about impact of vitamins on high blood pressure you need to know, and the powerful link between high blood pressure and a potassium-rich diet.

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