Study shows big cause of depression in middle-aged and older people

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Depression is one of the leading causes of disability worldwide, with middle-aged and older adults being especially vulnerable. A recent study from Colorado State University has revealed that social isolation is a major risk factor for depression in these age groups.

The researchers used machine learning to analyze data from a large group of middle-aged and older adults across Europe. This method allowed them to examine 56 variables to determine which factors most strongly predict depression.

The findings were clear: social isolation was the top risk factor for both men and women, followed by poor overall health and mobility challenges.

The study also explored 30 aspects of participants’ social lives, such as how often they interacted with friends and family, the size of their social network, and whether they gave or received help with physical care or finances.

These details helped the researchers better understand the role of relationships in mental health.

Interestingly, the study found some differences between men and women when it came to other key risks for depression. For men, difficulties with daily tasks like managing finances, taking medications, or making phone calls were significant.

In contrast, women who felt overwhelmed by family responsibilities were more likely to experience depression. For example, women who agreed with the statement, “Family responsibilities get in the way of my being able to do the things I want to do,” were at higher risk.

Despite these gender-specific differences, the researchers noted that these factors accounted for only a small part of the overall risk of depression. This highlights that social isolation and general health issues are far more important contributors for both genders.

The study’s authors emphasized the importance of addressing multiple risk and protective factors for depression, especially those related to social and relational support. Social isolation, they noted, can have varying effects depending on the individual’s circumstances.

For example, some people may be more vulnerable to isolation due to a lack of close connections, while others might feel isolated despite frequent interactions if those interactions lack emotional depth.

The findings suggest that reducing social isolation and improving access to supportive networks could significantly lower the risk of depression in middle-aged and older adults.

Encouraging meaningful social connections, promoting good health, and addressing mobility issues could be effective ways to support mental well-being in these populations.

This study, led by Stephen Aichele and published in The Lancet Regional Health—Europe, provides valuable insights into how social factors influence mental health.

It also highlights the importance of creating supportive environments where people feel connected and cared for, particularly as they age.

If you care about health, please read studies that scientists find a core feature of depression and this metal in the brain strongly linked to depression.

For more information about health, please see recent studies about drug for mental health that may harm the brain, and results showing this therapy more effective than ketamine in treating severe depression.

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