Medications help improve quality of life in ADHD, study finds

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Research from the University of Southampton has highlighted the significant role that medications play in improving the quality of life for people with Attention-Deficit/Hyperactivity Disorder (ADHD).

However, the authors of the study emphasize that medication alone is not enough, and additional support is necessary for those living with the condition.

The findings, published on August 8, 2024, in The Journal of the American Academy of Child and Adolescent Psychiatry, bring attention to the challenges posed by current shortages of certain ADHD medications.

Professor Samuele Cortese, the senior author of the study, expressed deep concern over the potential impact on individuals who are unable to access their medication due to supply issues or other barriers.

ADHD is characterized by symptoms such as inattention, hyperactivity, and impulsivity, which can severely affect a person’s social interactions, work performance, education, and ability to manage daily tasks.

According to Dr. Alessio Bellato, a lecturer in psychology at the University of Southampton and the lead author of the paper, people with ADHD often report a lower quality of life in areas like work productivity, social and family relationships, and self-esteem compared to those without the condition.

“This study shows that medications play an important role in improving quality of life for those with ADHD,” Dr. Bellato said.

The research conducted by the team involved a systematic review and meta-analysis of 17 placebo-controlled trials, involving over 5,000 participants.

These trials were sourced from the MED-ADHD dataset, the largest collection of ADHD medication trials, which was established by Professor Cortese and his international colleagues.

The study examined the effects of both stimulant medications (such as amphetamines and methylphenidate) and non-stimulant medications (such as atomoxetine) on the quality of life for individuals with ADHD.

The results showed that both stimulant and non-stimulant medications were significantly more effective than placebos in improving the quality of life for participants.

However, the study also revealed a disparity: while these drugs often have a medium to high impact on reducing the core symptoms of ADHD, their effect on improving overall quality of life was only in the small-to-medium range.

Professor David Coghill from the University of Melbourne, a co-author of the paper, pointed out that this gap suggests that merely addressing the core symptoms of ADHD through medication is unlikely to be sufficient to fully counteract the condition’s impact on quality of life.

He emphasized the need for further research to explore whether combining medication with other treatment approaches could lead to more substantial improvements in well-being. Additionally, identifying the most effective forms of support for individuals who cannot access medication is critical.

Dr. Bellato echoed the need for more research, particularly in understanding how ADHD medications affect quality of life.

He suggested that reducing the core symptoms of ADHD, such as inattention and hyperactivity, might lead to better task management and, consequently, improved academic and professional outcomes.

Moreover, medications may help stabilize emotional dysregulation, contributing to enhanced emotional well-being and higher self-esteem.

However, Dr. Bellato also acknowledged that ADHD medication might not be suitable or effective for everyone.

“Considering that ADHD medication might not be acceptable, effective, or well tolerated for everyone with ADHD, more research is needed to evaluate alternative approaches, including psychological interventions,” he said.

This study underscores the complexity of ADHD treatment and the importance of a holistic approach that goes beyond medication. As the research continues, the hope is to find more comprehensive strategies that can better support individuals with ADHD in improving their overall quality of life.

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The research findings can be found in the Journal of the American Academy of Child & Adolescent Psychiatry.

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