Scientists find why coffee affects everyone differently

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Have you ever wondered why some people can drink several cups of coffee and feel great, while others might feel jittery or have trouble after just one?

Researchers at the University of Toronto, led by Ahmed El-Sohemy, decided to explore this very question.

They focused on understanding how our genetic makeup influences our reaction to coffee, particularly looking at its effects on our kidneys.

Coffee is a popular beverage enjoyed by millions around the world. But not everyone processes caffeine—the main active ingredient in coffee—the same way.

This difference can largely be attributed to a specific gene called CYP1A2. This gene acts like a set of instructions for our body, telling it how to deal with caffeine.

Some people have a version of the CYP1A2 gene that processes caffeine very quickly. These individuals can drink coffee like it’s water, enjoying several cups a day without any negative effects.

On the other hand, some have a slower version of this gene. For these people, drinking too much coffee can lead to discomfort, especially for their kidneys, which play a crucial role in filtering and cleaning our blood.

The researchers found that the maximum amount of coffee considered safe for most people is about three cups per day. However, some can handle up to four cups without any problems.

Interestingly, the world’s population is roughly divided in half between those who have the fast-processing gene and those with the slow-processing gene.

What’s more, there’s a test available that can tell you whether you have the fast or slow version of the CYP1A2 gene. Knowing this can help you decide how much coffee you can drink safely, tailoring your caffeine intake to suit your body’s needs.

Understanding how our bodies react to what we consume is crucial for maintaining good health. This is especially important because everyone is different, and what works for one person might not work for another.

This study highlights the importance of a personalized approach to diet and health, recognizing our unique genetic makeup.

Our kidneys are essential to our health, cleaning our blood and helping remove toxins from our body. Keeping them healthy is vital and involves more than just monitoring our coffee consumption.

A balanced diet, regular exercise, staying hydrated, and careful use of medication all play a part in keeping our kidneys functioning well.

While we enjoy our daily coffee, scientists like Ahmed El-Sohemy are working hard to discover more about how different foods and substances affect our kidneys. They’re looking for foods that might protect our kidneys and developing new treatments to keep them healthy.

For those interested in learning more about these findings, the research team has published their work in the JAMA Network Open, offering a deep dive into how our genes can influence our health.

In essence, understanding how our bodies work helps us make better choices for our health. Whether our genetic makeup processes caffeine quickly or slowly, recognizing this can help us enjoy our coffee in a way that’s best for our body.

So, the next time you sip on your coffee, remember it’s not just a warm comforting beverage but also a subject of scientific study that helps us understand our health better. Let’s raise our mugs to more research that guides us in keeping our bodies healthy and happy!

If you care about wellness, please read studies about how ultra-processed foods and red meat influence your longevity, and why seafood may boost healthy aging.

For more information about wellness, please see recent studies that olive oil may help you live longer, and vitamin D could help lower the risk of autoimmune diseases.

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