Common side effects of cholesterol-lowering drugs

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Doctors often prescribe medicines to lower cholesterol as we get older, aiming to prevent heart problems and other age-related diseases.

The most well-known of these drugs are statins, like Lipitor and Crestor, which reduce the body’s cholesterol production. Another newer category is PCSK9 inhibitors, which help the body remove cholesterol from cells.

While these medications are effective at managing cholesterol levels, recent research has uncovered some unexpected side effects.

For instance, PCSK9 inhibitors may cause lung-related issues, although the long-term impacts require further study. Statins, on the other hand, have been linked to weight gain, increased body fat, and lower testosterone levels in some individuals.

Surprisingly, statins may also lead to an increase in the size of the hippocampus, the brain area critical for memory and emotions, potentially reducing the risk of dementia and depression.

This information comes from a study led by Kitty Pham, a Ph.D. student at the University of South Australia, who utilized genetic data to explore the effects of these drugs.

Genetic analysis allows researchers to predict how individuals with certain genetic markers might respond to these medications, revealing potential side effects like weight gain with statins.

Clinical trials, the traditional method for testing drug effects, are costly and time-consuming, particularly for assessing long-term impacts. Thus, genetic studies offer a valuable alternative for understanding how drugs might affect us over time.

It’s crucial to remember that medications are tools designed to maintain health, and their use should be carefully managed by healthcare professionals.

Discovering potential side effects doesn’t necessarily mean you should stop taking your medication. Instead, it highlights the importance of being informed and discussing any concerns or observed changes with your doctor.

Such findings underscore the need for ongoing research to fully understand the benefits and risks of cholesterol-lowering drugs.

This knowledge helps healthcare providers make informed treatment decisions and empowers patients to participate actively in their health care management.

The revelation of these side effects invites more research to better understand the mechanisms behind these medications and how they interact with our bodies.

It’s a step forward in personalized medicine, where treatments can be tailored to individual genetic profiles, optimizing benefits while minimizing risks.

Ultimately, studies like these contribute to a broader understanding of pharmaceuticals, enabling more effective and safer healthcare strategies for managing cholesterol and protecting against related health issues.

If you care about heart health, please read studies about the best time to take vitamins to prevent heart disease, and scientists find how COVID-19 damages the heart.

For more information about heart health, please see recent studies about Aspirin linked to higher risk of heart failure, and results showing Blackcurrants could improve artery functions, blood pressure in older people.

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