Promising therapy for heart failure patients with depression

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A recent study from Cedars-Sinai has brought new hope to heart failure patients suffering from depression.

This groundbreaking research demonstrates that behavioral activation therapy is just as effective as antidepressant medications for treating depressive symptoms in these patients.

Heart failure, affecting nearly 6 million adults in the U.S., is often accompanied by depression.

Half of the heart failure patients struggle with depressive symptoms, which worsen their cardiac function, increase hospital visits, and diminish the quality of life. The study’s findings offer an alternative treatment pathway for these patients.

Dr. Waguih W. IsHak, the vice chair of Education and Research at Cedars-Sinai and the study’s first author, emphasizes the significance of this discovery.

“Patients have a choice in their treatment,” he says, highlighting that those who prefer to avoid medication can opt for behavioral activation therapy with similar effectiveness.

Published in JAMA Network Open, the study followed over 400 patients for a year. It divided them into two groups: one receiving antidepressant medication and the other undergoing behavioral activation psychotherapy, a proven method for treating depression that encourages involvement in enjoyable activities.

The results were striking. Both groups saw a reduction of over 50% in the severity of depressive symptoms, with no significant difference in effectiveness between the two treatments.

Participants in the behavioral activation group worked with therapists to engage in activities they enjoyed, like having lunch with friends or volunteering.

This approach aimed to increase their participation in rewarding activities weekly for 12 weeks, then integrating them into their regular schedules.

Interestingly, patients in the psychotherapy group not only showed mental health improvements but also had fewer emergency visits and hospital stays than those on antidepressant medications.

This finding points to the broader benefits of integrating mental health care into medical treatment.

Dr. Itai Danovitch, the chair of the Department of Psychiatry and Behavioral Neurosciences at Cedars-Sinai and a co-author of the study, underscores the study’s real-world applicability.

He advocates for incorporating psychiatric treatment into medical care to reduce stigma, enhance access, and improve outcomes for patients dealing with mental health issues alongside chronic medical conditions.

The study’s implications are profound, particularly given that most people with depression don’t receive effective treatment.

Increasing screening for psychiatric conditions and ensuring access to quality mental health care are vital steps forward, as highlighted by the research team.

This study not only offers new treatment avenues for heart failure patients with depression but also reinforces the need for an integrated approach to health care.

The research findings can be found in JAMA Network Open.

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