Mixing blood pressure meds and ibuprofen may harm kidney health

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A recent study from the University of Waterloo brings to light an important health caution for individuals managing high blood pressure.

The research focuses on the interaction between common blood pressure medications and a popular painkiller, ibuprofen.

Many people with hypertension are prescribed a combination of diuretics and renin-angiotensin system (RSA) inhibitors. These medications are widely known under various brand names and work together to control high blood pressure.

Diuretics help the body reduce excess water, while RSA inhibitors play a role in managing the hormonal system that regulates blood pressure and fluid balance.

However, the study throws a spotlight on the potential risks of combining these medications with ibuprofen, a painkiller found in many over-the-counter drugs.

Ibuprofen is widely used for its effectiveness in relieving pain and is easily available in pharmacies and stores.

Using computer simulations to mimic drug interactions and their effects on the kidney, the researchers discovered that this combination could lead to acute kidney injury in some individuals. This type of kidney damage can be severe and, in certain cases, permanent.

It’s important to note that not everyone taking this combination of drugs will face health issues. But the study clearly indicates that there is a risk, and caution is advised.

This is especially relevant since many people might take ibuprofen for pain relief without considering its potential interaction with their blood pressure medication.

The research team points out that the risk arises from the fact that diuretics already reduce the body’s water content.

Being dehydrated is a key factor in developing acute kidney injury. When a RSA inhibitor and ibuprofen are added to the mix, it creates a ‘triple whammy’ effect on the kidneys.

For those on blood pressure medication needing a painkiller, the study suggests considering alternatives like acetaminophen, which does not have the same risky interaction with diuretics and RSA inhibitors.

Conducted by Anita Layton and her team, this research serves as a crucial reminder of the importance of being aware of how different medications can interact with each other.

It’s a call to action for individuals to be more mindful when combining pain relievers with their regular medication, particularly for conditions as common as high blood pressure.

If you care about high blood pressure, please read studies that early time-restricted eating could help improve blood pressure, and natural coconut sugar could help reduce blood pressure and artery stiffness.

For more information about blood pressure, please see recent studies about added sugar in your diet linked to higher blood pressure, and results showing vitamin D could improve blood pressure in people with diabetes.

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