Later menopause linked to better muscle strength in older women

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A new study published in Menopause reveals that the length of a woman’s reproductive life span, determined by her age at menarche (first menstruation) and menopause, can have a significant impact on her muscle mass and strength in later life.

This association sheds light on the importance of reproductive factors in women’s health beyond their role in fertility.

Sarcopenia and Its Impact

Sarcopenia is a condition characterized by a decline in skeletal muscle mass and function, often associated with the aging process.

It is projected that by 2045, approximately 72.4% of individuals aged over 65 worldwide will be affected by sarcopenia.

This condition can lead to reduced physical capability, decreased quality of life, cardiovascular issues, metabolic diseases, falls, disability, and even mortality.

Reproductive Factors and Muscle Health

Menarche and menopause are known to influence the aging process in women. Previous studies have indicated that postmenopausal women experience an annual loss of muscle mass.

One common method of assessing sarcopenia is by measuring handgrip strength. However, no prior research has explored the relationship between handgrip strength and the reproductive period.

In a recent study involving over 2,300 postmenopausal women aged 45 to 75 years, researchers discovered that a longer reproductive period was associated with a reduced risk of low handgrip strength.

This relationship remained significant even after accounting for other factors.

Factors that influenced handgrip strength included household income, education level, duration of breastfeeding, and intake of vitamin D and protein.

Although age at menopause was linked to reduced handgrip strength, no such relationship was observed for age at menarche.

It’s noteworthy that the prevalence of sarcopenia varies among postmenopausal women based on factors such as race and age. For instance, Asian women tend to experience sarcopenia less frequently.

Conclusion and Implications

This study highlights the connection between a woman’s reproductive life span and her muscle strength during the postmenopausal period.

A longer reproductive period and later age at menopause were associated with a lower risk of low handgrip strength in postmenopausal Korean women. This relationship may be attributed to the beneficial effects of estrogen on skeletal muscle.

Further longitudinal studies across diverse populations are needed to validate these findings and better understand the impact of reproductive factors on muscle health in women.

These insights emphasize the multifaceted nature of women’s health and the need for comprehensive healthcare strategies that consider various life stages and factors beyond reproduction.

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The research findings can be found in Menopause.

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