Psychiatric disorders common in dementia patients prior to diagnosis

Credit: Unsplash+

Dementia is a condition that affects millions of people around the world, primarily impacting memory, thinking, and behavior.

But could there be signs of psychiatric disorders before dementia is officially diagnosed? A recent study delved into this question and uncovered some intriguing findings.

Before we dive into the study’s results, it’s important to understand what dementia is. Dementia isn’t a single disease but a broad term for various cognitive impairments that interfere with a person’s daily life.

Alzheimer’s disease is one of the most common types of dementia, but there are others, such as vascular dementia and mixed dementia. Dementia can affect memory, thinking, and behavior, and it can be challenging for both patients and their families.

Researchers at the Karolinska Institutet in Stockholm conducted a study to investigate the relationship between dementia and psychiatric disorders.

They wanted to know if there was an increased risk of psychiatric conditions in the years leading up to a dementia diagnosis, at the time of diagnosis, and afterward.

Higher Risk Before and After Diagnosis

The study involved a vast number of individuals—over 796,000 people, including 209,000 with dementia. The researchers compared the risk of psychiatric disorders in dementia patients with those without dementia. Here’s what they found:

The risk of psychiatric disorders began to increase three years before a dementia diagnosis.

The risk reached its peak the week after a dementia diagnosis, with patients being nearly five times more likely to experience psychiatric disorders during that time.

After the peak, the risk of psychiatric disorders decreased rapidly but remained higher for dementia patients than for those without dementia.

These patterns were consistent across different types of dementia, including Alzheimer’s disease and vascular dementia.

Medications and Depression

The study also looked at medication use and found that in the year leading up to a dementia diagnosis, there was a significant increase in the use of psychiatric medications. This increase peaked six months after the diagnosis.

Notably, the use of antidepressants was consistently higher among dementia patients compared to those without dementia. This difference started to show two years before a dementia diagnosis.

What Does It All Mean?

So, what can we take away from this study? It suggests that individuals with dementia have an elevated risk of developing psychiatric disorders before and after their diagnosis.

Managing these psychiatric comorbidities is crucial for dementia patients at various stages of the disease.

It’s essential to recognize that dementia is a complex condition that affects more than just memory and cognitive abilities. It can have far-reaching effects on a person’s mental and emotional well-being.

Therefore, providing comprehensive care and support for individuals with dementia, including addressing psychiatric disorders, is of paramount importance.


Dementia is a challenging condition, both for those who have it and for their loved ones. This study sheds light on the increased risk of psychiatric disorders in dementia patients leading up to and following their diagnosis.

By understanding these patterns, healthcare providers can better tailor their care to address not only the cognitive aspects of dementia but also the associated psychiatric challenges, ultimately improving the quality of life for those affected by this condition.

If you care about dementia, please read studies about low choline intake linked to higher dementia risk, and how eating nuts can affect your cognitive ability.

For more information about brain health, please see recent studies that blueberry supplements may prevent cognitive decline, and results showing higher magnesium intake could help benefit brain health.

The research findings can be found in JAMA Network Open.

Follow us on Twitter for more articles about this topic.

Copyright © 2023 Knowridge Science Report. All rights reserved.