New device and medication combo can treat heart failure at home

Credit: European Heart Journal - Cardiovascular Pharmacotherapy (2023). DOI: 10.1093/ehjcvp/pvad073

A groundbreaking device and medication combination developed by SQ Innovation Inc and tested by the University of Glasgow Heart Failure Clinical Trial Team has the potential to revolutionize heart failure treatment.

The results of two landmark patient studies suggest that this innovative combination is safe and effective, allowing patients to receive treatment at home.

Heart failure, a condition where the heart doesn’t pump blood efficiently, often results in fluid accumulation in the lungs or legs.

Current treatment involves diuretic tablets, but if swelling and fluid build-up persist, patients require hospitalization for intravenous medication. These extended hospital stays can be burdensome for patients and the healthcare system.

The two clinical trials explored a new subcutaneous formulation of furosemide, a diuretic drug, designed to be self-administered by patients at home.

The first study demonstrated the effectiveness of the new furosemide, showing it to be as effective as traditional treatment with minimal side effects. The second trial examined the combination of the new drug with an innovative mini pump designed by SQ Innovation Inc.

This pump, fitted with a small needle, delivers the drug under the patient’s skin to reduce fluid build-up. The research found that this combination of the new drug and device was both safe and effective.

The results of these studies have paved the way for a larger study in which patients hospitalized with fluid excess due to heart failure are offered the new medication and pump for at-home use.

This development has the potential to improve the lives of heart failure patients and reduce the strain on hospital beds by eliminating the need for extended inpatient treatment.

Patients who participated in the trials reported positive experiences with the new device and medication, highlighting its ease of use, comfort, and the freedom it afforded them in managing their daily lives.

The combination’s potential to provide flexibility and improved quality of life for heart failure patients is a significant advancement in healthcare.

The research study was published in the European Heart Journal—Cardiovascular Pharmacotherapy, offering promising results for the future of heart failure treatment.

If you care about heart health, please read studies about Scientists find root cause of heart rhythm disorders and findings of Warning signal from the kidneys can predict future heart failure risk.

For more information about heart health, please see recent studies that apple juice could benefit your heart health, and results showing yogurt may help lower the death risks in heart disease.

The research findings can be found in European Heart Journal—Cardiovascular Pharmacotherapy.

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