Running or medicine, which is better for treating depression?

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Unpacking Choices for Mental Health

Depression and anxiety weigh heavily on countless individuals, prompting the exploration of diverse treatment options.

A study led by Professor Brenda Penninx at Vrije University, Amsterdam, delved into contrasting the effects of antidepressants and running exercises on 141 patients, offering an insightful peek into the merits of both approaches towards managing mental and physical health.

Two Paths to Better Mental Health

Participants, battling with depression and/or anxiety, were provided a choice between two 16-week treatments: SSRI antidepressants or supervised running therapy.

Intriguingly, a majority (96) opted for running, whereas 45 chose antidepressants.

At the culmination of the trial, both groups displayed roughly a 44% improvement in their mental health conditions. However, their physical health paths diverged notably.

The group that chose to run evidenced enhancements in aspects like weight, waist circumference, blood pressure, and heart function.

Contrastingly, those who took antidepressants, specifically Escitalopram, witnessed a slight decline in these metabolic markers, affirming suspicions about the drug’s impact on physical health despite its efficacy in alleviating mental health issues.

Professor Penninx remarked, “Both interventions helped with depression to around the same extent. Antidepressants generally had worse impact on body weight, heart rate variability and blood pressure, whereas running therapy led to improved effect on general fitness and heart rate for instance.”

Adherence: A Hurdle for Healthy Habits

While the majority expressed a preference for exercise, a stark contrast was noticed in adherence between the two groups.

A commendable 82% of the antidepressant group stuck to their prescribed medication intake, whereas only 52% of the running group maintained their exercise regimen consistently throughout the 16 weeks.

Penninx highlighted, “Telling patients to go run is not enough. Changing physical activity behavior will require adequate supervision and encouragement as we did by implementing exercise therapy in a mental health care institution.”

These figures accentuate the glaring challenge in encouraging consistent lifestyle changes, even when individuals are aware of their benefits.

A Holistic View of Patient Care

While antidepressants have been established as generally safe and effective, and undeniably beneficial to numerous individuals, the study underscores the importance of diversifying available treatments and taking a holistic view of patient health.

Penninx underscored the pertinence of considering potential side effects and being mindful of the physical health implications of antidepressants, particularly in individuals with existing health concerns like heart issues.

“In the end, patients are only truly helped when we are improving their mental health without unnecessarily worsening their physical health,” she noted.

Thoughtful Reflections

Dr. Eric Ruhe, of Amsterdam University Medical Centers, emphasized the importance of choice in treatment, while also noting the potential biases present when participants select their preferred treatment method.

He indicated the need for caution in interpreting the comparative data due to variables like the differing levels of depression in the groups.

Moreover, he spotlighted the challenge of lifestyle change adherence, stating, “This shows that it is more difficult to change a lifestyle habit than taking a pill.”

Dr. Ruhe’s reflections signal the universal struggle in adopting and maintaining healthy habits, elucidating an arena that warrants further exploration in psychiatric research and beyond.

In navigating the intricate journey of managing mental health, the findings beckon healthcare professionals to view treatment through a comprehensive lens, recognizing the entwined paths of mental and physical wellbeing and the challenges posed by adherence to lifestyle changes.

As we forge ahead, studies like these light the way towards more personalized, considerate, and holistic approaches in grappling with the complexities of mental health care.

If you care about health, please read studies that scientists find a core feature of depression and this metal in the brain strongly linked to depression.

For more information about health, please see recent studies about drug for mental health that may harm the brain, and results showing this therapy more effective than ketamine in treating severe depression.

The research findings can be found in the Journal of Affective Disorder.

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