Why one antibiotic can treat acne best

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Pimples. Yep, we’ve all had them. They pop up on our faces when we least want them and are an absolute pain.

Especially during our teenage years, we look at ourselves in the mirror and wish for a magic wand to make them vanish.

Don’t worry; it’s not just you! In fact, acne, the scientific term for pimples, is one of the most common diseases affecting humans. Around 85% of young people struggle with it. Sounds crazy, right?

Battling Acne With Antibiotics: Yay or Nay?

Doctors have long been using antibiotics, the tiny germ killers, to help us fight against this skin condition. These are handy as they kill the germs that cause acne and also reduce swelling.

But here’s the tricky part – not all germs are bad. Our bodies are filled with trillions of germs, and many of them are actually good for us.

When we take antibiotics, they can sometimes kill these good germs too. That’s like firing a cannon to kill a mosquito – you get rid of the mosquito, but you also create a mess!

The Problem with the ‘Germ-Cannon’ Approach

Doctors have been using a type of antibiotic known as broad-spectrum for a long time. Just like wide-net fishing, these antibiotics catch all kinds of germs – the bad ones and the good ones.

It’s like trying to catch one particular fish but ending up with a net full of all sorts of marine life. These drugs, even if taken for a short while, can mess up your good bacteria for up to two years!

That’s like having your lawn destroyed and waiting two long years for it to become green again.

A New Hero for Acne – Sarecycline

But here’s the good news. Some smart scientists at Yale University have been busy studying a new kind of antibiotic named Sarecycline.

Unlike the broad-spectrum antibiotics that act like a big, clumsy cannon, this new drug works more like a sniper, taking out the exact bacteria causing acne without harming the friendly ones.

Imagine having a smart, guided missile that only targets the enemy and leaves your friends unharmed!

How Does Sarecycline Do Its Magic?

The Yale team, led by a cool doctor-scientist, Christopher Bunick, went on a detective mission to figure out how this drug works.

They found out that it acts like a double-agent, binding itself to not just one, but two sites on the harmful bacteria. It’s like having two keys to open a door, making it twice as hard for the bacteria to become resistant to the drug.

Bringing Zinc into the Picture

Now, the story gets even more exciting. While investigating Sarecycline, the team found something interesting about zinc, a mineral you might have heard about in your multivitamin supplements.

They found that bad bacteria have proteins that can bind with zinc. Some people believe taking zinc can help with acne, and this finding adds some science to that idea.

Think of it like adding a special fertilizer to make your lawn greener and healthier!

A Closer Look at Our Acne Enemy

The scientists used a high-tech tool called cryo-EM (don’t worry about the full form, it’s just a super microscope) to get a detailed view of the acne-causing bacteria.

This is the first time anyone has ever seen this germ in such detail, kind of like getting a HD look at an alien from a different planet!

Understanding the Game to Win It

Dr. Bunick and his team are like acne detectives. They’re trying to understand exactly how this acne drug works.

They believe that if we understand the enemy (in this case, acne), we can fight it better. This research is a big leap toward that understanding. It’s like cracking the code of a secret message!

Final Words

The moral of the story is – understanding how a medicine works can help us use it better. Just like how knowing your car can help you drive it better and keep it in good shape.

By understanding acne and the drugs used to treat it, we can hope for better and more efficient treatments in the future. We might not have that magic wand yet, but we’re definitely getting closer!

If you care about health, please read studies about antibiotics linked to higher colon cancer risk, and this yogurt may prevent diarrhea caused by antibiotics.

For more information about health, please see recent studies about the key to improving longevity in older people, and results showing intense meditation strongly boosts the immune system.

The study was published in Nucleic Acids Research.

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