Scientists uncover an important cause of chronic inflammation

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A recent study by the University of South Australia has identified a direct relationship between low levels of vitamin D and high levels of inflammation.

The study offers crucial insights that may help identify individuals at heightened risk or severity of chronic diseases with an inflammatory component.

The research examined the genetic data of nearly 295,000 participants in the UK Biobank and utilized Mendelian randomization to demonstrate the association between vitamin D and C-reactive protein levels, a common marker of inflammation.

Inflammation is a crucial aspect of the body’s healing process. However, when persistent, it can contribute to a host of complex diseases, including type 2 diabetes, heart disease, and autoimmune disorders.

C-reactive protein levels increase in the liver in response to inflammation. Chronic inflammation results in consistently high levels of this protein.

The research team found a one-way relationship between low levels of vitamin D and increased levels of C-reactive protein, indicative of inflammation.

This discovery implies that increasing vitamin D in individuals with a deficiency may help alleviate chronic inflammation, possibly aiding them in avoiding related diseases.

The study also proposes that adequate concentrations of vitamin D may alleviate complications stemming from obesity and reduce the risk or severity of chronic illnesses with an inflammatory component, such as cardiovascular diseases, diabetes, and autoimmune disorders.

The research team emphasized the significance of these findings and offered them as a clarification for some of the controversies in reported associations with vitamin D.

The research was led by Dr. Ang Zhou and published in the International Journal of Epidemiology.

These findings provide a new avenue for mitigating the risks associated with chronic diseases by addressing vitamin D deficiencies.

If you care about inflammation, please read studies about the cause of severe inflammation in COVID-19, and inflammation drugs could help prevent COVID-19 deaths.

For more information about health, please see recent studies about dieting methods that can effectively reduce inflammation, and results showing that inflammation may actually slow down cognitive decline in older people.

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