AI could help find best treatment for high blood pressure

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A new artificial intelligence (AI) program may aid doctors in better-matching individuals with high blood pressure (hypertension) to the most suitable medication for their condition.

Hypertension, affecting nearly half of Americans, led to almost 700,000 deaths in 2021, according to the US Centers for Disease Control and Prevention.

Published in BMC Medical Informatics and Decision Making, the study describes a data-driven model that generates real-time hypertension treatment recommendations based on patient-specific characteristics, including demographics, vital signs, medical history, and clinical test records.

The AI model produces a personalized hypertension prescription using the patient’s profile, suggesting a list of medications with an associated probability of success.

The aim is to highlight the treatment that best controls systolic blood pressure based on its effectiveness in similar patients.

Developed using de-identified data from 42,752 hypertensive patients collected between 2012 and 2020, the model sorts patients into affinity groups based on clinically relevant characteristics.

The model achieved a 70.3% larger reduction in systolic blood pressure than standard care and outperformed three other predictive algorithms.

This model represents a significant advancement in the use of AI in healthcare, with the potential to improve treatment outcomes and the quality of care delivered.

However, the adoption of AI in healthcare has been limited due to difficulties interpreting the results and a lack of trust in artificial intelligence.

Personalized medicine approaches like this offer a promising opportunity to better serve populations that aren’t adequately represented in national studies or considered when formulating guidelines.

The researchers hope to maximize the effectiveness of hypertensive medications at the individual level.

If you care about high blood pressure, please read studies about which blood pressure number matters most, and this blood pressure drug may increase the risk of sudden cardiac arrest.

For more information about blood pressure, please see recent studies about new ways to treat drug-resistant high blood pressure, and results showing this common snack may cause heart rhythm disease, and high blood pressure.

The study was published in BMC Medical Informatics and Decision Making.

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