Diabetes drug may reduce dementia risk, study suggests

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The Link Between Diabetes and Dementia

Did you know that people with diabetes are more likely to develop dementia? Dementia is a condition that affects a person’s memory and thinking skills.

But there’s new hope! A recent study found that a diabetes drug called pioglitazone may help reduce the risk of dementia in people with newly diagnosed type 2 diabetes.

The Study and its Findings

The study looked at a large group of people in Korea who were newly diagnosed with type 2 diabetes and did not have dementia.

They were followed for about 10 years to see what happened. Out of the over 91,000 participants, some took the diabetes drug pioglitazone, while others did not.

The researchers found that those who took pioglitazone were less likely to develop dementia compared to those who did not take the drug.

About 8.3% of the people taking pioglitazone developed dementia, while 10.0% of those not taking the drug developed it. This means that taking pioglitazone reduced the risk of dementia by 16%.

Even More Benefits

The study also found that the longer people took the drug, the lower their risk of dementia.

Those who took pioglitazone for four years had a 37% lower risk of dementia compared to those who did not take the drug.

Even taking it for just one to two years reduced the risk by 22%. Isn’t that amazing?

Not only did the drug help with dementia, but it also lowered the risk of having a stroke during the study. This is important because people with diabetes are more likely to have strokes.

Who Benefits the Most?

The researchers found that the benefits of pioglitazone were even stronger for people who had a history of ischemic heart disease or stroke.

For those with ischemic heart disease, the risk of dementia was reduced by 54%, and for those with a history of stroke, it was reduced by 43%.

So, if someone has diabetes and a history of these conditions, taking pioglitazone may be even more beneficial for them.

Considerations and Future Research

It’s important to note that this study only shows an association between pioglitazone and reduced dementia risk. It doesn’t prove that the drug directly causes this effect.

Also, pioglitazone has some side effects, such as swelling and weight gain, so more research is needed to understand the long-term safety of the drug.

Further studies are also needed to confirm these findings and to see if there is an optimal dose of the drug that can minimize side effects while still providing the benefits.

It’s essential to continue exploring ways to prevent and treat dementia, especially in people with diabetes.

In Conclusion

This study gives hope to people with newly diagnosed type 2 diabetes. Taking the diabetes drug pioglitazone may help reduce the risk of developing dementia.

However, it’s always important to talk to a doctor before starting any new medication. With more research, we can continue to find ways to protect our brain health and improve the lives of people living with diabetes.

If you care about diabetes, please read studies that MIND diet may reduce risk of vision loss disease, and Vitamin D could benefit people with diabetic neuropathic pain.

For more information about diabetes, please see recent studies that Vitamin E could help reduce blood sugar and insulin resistance in diabetes, and results showing eating eggs in a healthy diet may reduce risks of diabetes, high blood pressure.

The study was published in Neurology.

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