Common diabetes drug may increase heart failure risk

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Rosiglitazone belongs to a class of drugs called thiazolidinediones, a new class of drugs for the treatment of type 2 diabetes.

In a recent study from Yale School of Public Health, scientists found evidence that drug rosiglitazone is linked to an increased risk of heart problems, especially heart failure.

This study is the most comprehensive evaluation of the heart risk of rosiglitazone ever done.

Rosiglitazone helps control blood sugar levels in patients with type 2 diabetes, but it can also increase the risk of serious heart problems.

This has led to a suspension of the drug in Europe and previous restrictions on its use in the United States.

However, since 2007, studies have reported conflicting findings of whether rosiglitazone increases the risk of heart attacks.

But these studies didn’t have access to individual patient-level data and are not as reliable when estimating the true safety profile of drugs.

In the study, the team analyzed the results of more than 130 trials involving over 48,000 adult patients that compared rosiglitazone with any control for at least 24 weeks.

They found rosiglitazone was linked to a 33% increased risk of a composite cardiovascular event (heart attack, heart failure, cardiovascular and non-cardiovascular related death) compared with controls.

This was estimated from the 274 events among 11,837 rosiglitazone patients and 219 events among 9,319 control patients.

The team says these findings highlight the potential for different results derived from different data sources.

They also demonstrated the need for greater clinical trial transparency and data sharing to accurately assess the safety of drugs.

If you care about diabetes, please read studies about high vitamin D levels linked to lower risk of type 2 diabetes, and Mediterranean diet could help reduce the diabetes risk by 30%.

For more information about heart health, please see recent studies that blackcurrants can reduce blood sugar after meal and results showing how drinking milk affects risks of heart disease and cancer.

The study was published in the BMJ.

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