Inflammatory bowel disease may cause psoriasis, psoriatic arthritis

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Inflammatory Bowel Disease is a broad term that describes conditions characterized by chronic inflammation of the gastrointestinal tract.

The two most common inflammatory bowel diseases are Crohn’s disease and ulcerative colitis.

Psoriasis is a chronic autoimmune skin disease that speeds up the growth cycle of skin cells. Psoriatic arthritis is an inflammatory type of arthritis that eventually occurs in 10% to 20% of people with psoriasis.

In a study from the University of Augsburg, scientists found there seems to be a causal effect between inflammatory bowel disease and psoriasis, psoriatic arthritis.

They examined the association between inflammatory bowel disease and psoriasis or psoriatic arthritis.

The team used data from genome-wide association studies, which included up to 463,372 European people. The European samples included 12,882 inflammatory bowel disease cases and 5,621 psoriasis cases.

The researchers found that the risks for psoriasis and psoriatic arthritis were increased with genetically predicted inflammatory bowel disease.

Crohn’s disease subentity was associated with psoriasis and psoriatic arthritis, while ulcerative colitis was not. No notable associations were identified in the reverse directions.

The team says the results of the study are critical because raising awareness among clinicians and primary care physicians about the potential risk of psoriasis in patients with inflammatory bowel disease will contribute to systematic diagnosis and interdisciplinary and early personalized treatment of patients.

If you care about bowel health, please read studies about food linked to a higher risk of inflammatory bowel disease, and meds for common bowel disease may protect against severe COVID-19.

For more information about bowel health, please see recent studies that ultra-processed food could increase the risk of inflammatory bowel disease, and results showing scientists find a new treatment for inflammatory bowel disease.

The study was conducted by Dennis Freuer et al and published in JAMA Dermatology.

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