Scientists from the University of Dundee found that protection against heart attack, stroke, and vascular death is not affected by whether high blood pressure medications are taken in the morning or evening.
More than one billion people have high blood pressure worldwide.
High blood pressure is the leading global cause of premature death, accounting for almost ten million deaths in 2015, of which 4.9 million were due to ischemic heart disease and 3.5 million were due to stroke.
Nocturnal blood pressure is a better predictor of heart outcomes than daytime blood pressure.
There is previous evidence that blood pressure drugs taken in the evening rather than in the morning reduced night-time blood pressure to a greater extent.
In the study, the team examined more than 21,000 patients with high blood pressure followed for over five years.
10,503 were assigned to evening dosing and 10,601 to morning dosing.
The team did not meaningful differences in heart health and blood pressure results between the two groups. They also found taking medication in the evening was not harmful.
The study clearly found that heart attack, stroke, and vascular death occurred to a similar degree regardless of the time of administration.
People with high blood pressure should take their regular blood pressure medications at a time of day that is convenient for them and minimizes any undesirable effects.
The new finding is contrary to one of the largest heart studies ever conducted and provides a definitive answer to the question of whether blood pressure lowering medications should be taken in the morning or evening.
If you care about blood pressure, please read studies about how to treat slightly high blood pressure, and cherry concentrate can lower blood pressure as much as drugs.
For more information about blood pressure, please see recent studies about the best high blood pressure treatment for stroke patients, and results showing extra virgin olive oil could lower blood pressure.
The research was presented at ESC Congress 2022 and conducted by Thomas MacDonald et al.
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