Scientists from the University of Otago found how exercise can reduce the chance of diabetes leading to heart disease.
The research identified that exercise triggers the release of small sequences of genetic code in the heart called microRNA, which increases protein production to improve heart structure and function.
The team found that specific microRNA is adversely altered in the early stages of diabetes. These altered microRNA can reliably predict the inevitable onset of heart disease.
This is a pivotal new development as microRNA can serve as a reliable early biomarker for heart disease in diabetes.
The team says they’ve proven that by using exercise as a treatment, we can increase good microRNA, and reduce bad microRNA from causing damage.
Exercise effectively improves the regulation of microRNA to prevent the onset and progression of heart disease.
Along with highlighting the role of exercise in regulating microRNA, the study also shows that microRNA is a potential novel target for the therapeutic treatment of heart disease in people with chronic diabetes.
The team believes this research has clear long-term benefits on both the quality of life for diabetic patients with heart disease, as well as alleviating the economic burden associated with the current treatment of diabetes.
By understanding the physiological role of microRNA scientists can see without doubt the positive role of exercise in preventing diabetic heart disease.
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The research was published in the journal Circulation Research and conducted by Associate Professor Daryl Schwenke et al.
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