In a recent study, scientists found that people with glomerular disease have higher risks of heart attack and stroke.
Glomerular diseases damage the glomeruli, letting protein and sometimes red blood cells leak into the urine.
Sometimes a glomerular disease also interferes with the clearance of waste products by the kidney, so they begin to build up in the blood.
Primary glomerular disease means that the condition occurs on its own, without another known systemic disease such as lupus or diabetes.
Patients with chronic kidney disease are known to be at high risk of heart disease.
Heart risk in patients with primary glomerular diseases is poorly understood because these conditions are rare and require a kidney biopsy for diagnosis.
In the study, the team examined almost 2,000 adults with primary glomerular disease and followed them for about 7 years.
The team found risks of heart attack and stroke and death were 2.5 times as high as the general population.
They also found the consideration of disease type, kidney function, and proteinuria improved the prediction of heart events.
These findings showed that patients with primary glomerular diseases have a high heart disease risk, and that inclusion of kidney-specific risk factors may improve risk stratification.
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The research was published in the American Journal of Kidney Diseases.
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