Scientists from the University of Rome ‘Tor Vergata’ and elsewhere confirm that gut microbiota plays a big role in autism spectrum disorder (ASD).
The research is published in Neuroscience and was conducted by Ennio Avolio et al.
ASD is a neurological and developmental condition that affects how humans communicate, learn new things and behave.
Symptoms of ASD can include difficulties in interacting with others and adapting to changes in routine, repetitive behaviors, irritability and restricted or fixated interests for specific things.
Recent studies have found that the biological makeup of the gut could contribute to some of the most characteristic symptoms of ASD.
In the study, the team examined the effects of transplanting fecal microbiota gathered from autistic donors to mice.
They found fecal microbiota transplant (FMT) via gavage from autistic children donors to mice, led to the colonization of ASD-like microbiota and autistic behaviors.
Such variations seemed to be tightly linked to increased populations of Tenericutes plus a notable reduction of Actinobacteria and Candidatus S.
Essentially, the team examined two different groups of mice. Mice in the first group (i.e., the experimental group) received transplanted microbiota originating from the gut of children with ASD, while mice in the other (i.e., the control group) were exposed to VPA, a synthetic compound with anticonvulsant properties, while in their mothers’ wounds.
Interestingly, the team found that the mice who received the ASD microbiota exhibited unusual behaviors linked to those observed in children and adults with ASD.
The recent findings confirm previous results in the field, suggesting that gut microbiota can indeed play a role in social behaviors in ASD.
In the future, they could inspire new research in this area and contribute to the testing and gradual introduction of treatments for autism that also consider diet and gut health.
If you care about gut health, please read studies that your vitamin D level may affect your gut health, and COVID-19 virus can be found in gut 7 months after infection.
For more information about gut diseases, please see recent studies that your gut holds the key to treating type 2 diabetes, and results showing this diet can boost your gut health effectively.
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