In a new study from Hamilton Health Sciences in Canada, researchers found for patients with type 2 diabetes and a history of heart disease or current kidney disease, the risk for adverse heart events is lower with the drug efpeglenatide.
They examined efpeglenatide in people with type 2 diabetes.
Participants were randomly assigned to receive weekly injections of efpeglenatide (2,717 participants) at a dose of 4 or 6 mg or placebo (1,359 participants).
The researchers found that adverse heart disease events occurred in 7% and 9.2% of those receiving efpeglenatide and placebo, respectively, during a 1.8-year following period.
Kidney problems occurred in 13% and 18.4% of those randomly assigned to receive efpeglenatide and placebo, respectively.
The team says they are encouraged that this once-a-week injection safely and effectively reduced heart problems and kidney disease in patients with long-standing diabetes who had a high prevalence of cardiovascular and kidney disease.
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The study is published in the New England Journal of Medicine. One author of the study is Hertzel C. Gerstein, M.D.
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