Scientists find the best ways to limit COVID-19 spread

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In a new study, researchers found that less-intrusive, non-pharmaceutical interventions (NPIs) to limit the spread of COVID-19, such as effective communication strategies and government support, may be just as effective in slowing transmission as more intrusive solutions, such as lockdowns.

They did an assessment of interventions taken in a variety of countries and regions between March and April 2020.

They also found that the most effective NPIs were the cancelation of small gatherings, closure of educational establishments, border restrictions, individual movement restrictions, national lockdowns, and increasing the supply of personal protective equipment.

In the absence of an effective vaccine to treat COVID-19, NPIs are being used by governments to mitigate the spread of the virus.

As these interventions have economic and social impacts, understanding which NPIs are the most effective would allow stakeholders to target interventions to reduce the transmission rate.

In the study, the team used four computational methods to model the effect of 6,068 NPIs, implemented between March and April 2020 in 79 countries or regions, to assess their impact on mitigating the spread of COVID-19 and reducing the reproduction rate.

They then validated these results using two external databases of 42,151 NPIs from 226 countries.

All four methods identified the same NPIs (the cancelation of small gatherings, closure of educational establishments, border restrictions, individual movement restrictions, national lockdowns, and increasing the supply of personal protective equipment) as being most effective.

Additionally, the researchers also identified that less-disruptive NPIs, including governmental support to vulnerable populations, food assistance programs, and communication strategies on social distancing and self-isolation, can be as effective in reducing the rate of transmission as more drastic and intrusive options, such as lockdowns.

Among the least effective NPIs were environmental measures, such as the cleaning of shared surfaces.

The team found that the effectiveness of NPIs in individual countries was affected by the speed of implementation, how many measures had already been implemented, and socioeconomic, cultural, and political factors.

The researchers highlight that there is no individual NPI that will prevent the spread of COVID-19 and that a combination of interventions tailored to an individual country and its epidemic is needed.

They caution that their data is time-limited, and further research is needed to assess the impact of the NPIs over a longer period when countries were easing and/or re-implementing restrictions.

One author of the study is Peter Klimek.

The study is published in Nature Human Behavior.

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