In a new study, researchers found higher bisphenol A (BPA) exposure is associated with an increased risk for all-cause mortality in a nationally representative cohort of U.S. adults.
The research was conducted by a team at the University of Iowa in Iowa City.
The team conducted a nationally representative study involving 3,883 adults aged 20 years or older from the U.S. National Health and Nutrition Examination Survey 2003 to 2008 who provided urine samples for BPA level measurements.
The researchers found 344 deaths during 36,514 person-years of follow-up, including 71 deaths from heart disease and 75 deaths from cancer.
The risk for death was higher for participants with higher urinary BPA levels.
Comparing the highest versus the lowest level of urinary BPA levels, the team found tiger BPA exposure was linked to higher risks of all-cause mortality, heart disease mortality, and cancer mortality.
These findings were seen after adjustment for many variables, including age, sex, race/ethnicity, socioeconomic status, dietary and lifestyle factors, body mass index, and urinary creatinine levels.
The team says the association between BPA exposure and heart disease mortality needs further investigation.
In addition, further studies are needed to replicate these findings in other populations and determine the underlying mechanisms.
One author of the study is Wei Bao, M.D., Ph.D. from the College of Public Health.
The study is published in JAMA Network Open.
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