Recently, researchers from UCLA’s Jonsson Comprehensive Cancer Center have developed a new method to treat pancreatic cancer.
They found a new treatment combination may help fight pancreatic cancer effectively.
They hope the finding could benefit people with pancreatic cancer and help them live longer.
Pancreatic cancer occurs when cells in the pancreas begin to multiply out of control and form a mass.
The cancer cells can invade other parts of the body to become resistant to treatments that work in treating other cancers.
Currently, there is no treatment to deal with pancreatic cancer.
In this study, the researchers wanted to understand how the cancer cell pathways work and find potential new therapies.
They combined chloroquine that is used to treat malaria with more than 500 different inhibitors to screen for any interactions that could yield a cancer-fighting effect.
The result showed a complementary inhibitor called replication stress response inhibitor.
Based on the result, the team developed a drug combination.
The new drug combo includes one drug that inhibits the process that allows cancer cells to survive and another drug that blocks the pathway can cancer use to repair DNA.
It was promising in tests on pancreatic cancer cells and mice.
The new finding provides evidence that using chloroquine in combination with an inhibitor could reduce tumor growth in pancreatic cancer.
The team hopes their drug combo can lead to new treatment strategies for the disease.
The finding also shows how existing drugs could work and help treat other diseases.
The study is published in the Proceedings of the National Academy of Sciences.
Scientists suggest that to prevent pancreatic cancer, people can do several things:
Prevent type 2 diabetes and obesity. If you have a healthy weight, try to maintain it.
Do not smoke. Researchers suggest that smoking is the most important avoidable risk factor for pancreatic cancer. Quitting smoking can help lower the risk of many chronic diseases and increase the quality of life.
Drinking less alcohol. Heavy alcohol use can lead to conditions such as chronic pancreatitis and cirrhosis, which may increase pancreatic cancer risk.
Eat a healthy diet. Eating plenty of healthy grains, vegetables, and fish, as well as limiting red meat and sweets, has been shown to lower the risk of pancreatic cancer.
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